RECRUITING

Exercise Effects on Adipose Tissue Structure and Function

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.

Official Title

Exercise Effects on Adipose Tissue Structure and Function

Quick Facts

Study Start:2021-03-01
Study Completion:2030-03-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04812314

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age: 18-40
  2. * Body Mass Index: 27-45 kg/m2
  3. * No regularly planned exercise/physical activity for at least 6 months
  4. * Women must have regularly occurring menses and must be premenopausal
  1. * Evidence/history of cardiovascular or metabolic disease
  2. * Medications known to affect lipid or glucose metabolism, or inflammation
  3. * Weight instability ≥ ± 6 pounds in the last 3 months
  4. * Tobacco or e-cigarette users
  5. * Women must not be pregnant or actively lactating

Contacts and Locations

Study Contact

Suzette Howton
CONTACT
734-647-9850
smlstudies@umich.edu

Principal Investigator

Jeffrey F Horowitz, PhD
PRINCIPAL_INVESTIGATOR
University of Michigan, School of Kinesiology

Study Locations (Sites)

University of Michigan
Ann Arbor, Michigan, 48109
United States

Collaborators and Investigators

Sponsor: University of Michigan

  • Jeffrey F Horowitz, PhD, PRINCIPAL_INVESTIGATOR, University of Michigan, School of Kinesiology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-03-01
Study Completion Date2030-03-01

Study Record Updates

Study Start Date2021-03-01
Study Completion Date2030-03-01

Terms related to this study

Additional Relevant MeSH Terms

  • Obesity
  • Metabolic Syndrome
  • Metabolic Disease
  • Insulin Resistance
  • Weight Loss
  • Weight Gain