Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Description

The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence of atrial fibrosis on Delayed Enhancement Magnetic Resonance Imaging (DE-MRI) in OSA patients without atrial fibrillation (AF).

Conditions

Atrial Fibrillation, Obstructive Sleep Apnea

Talk to us

Study Overview

On this page

Study Details

Study overview

The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence of atrial fibrosis on Delayed Enhancement Magnetic Resonance Imaging (DE-MRI) in OSA patients without atrial fibrillation (AF).

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Condition
Atrial Fibrillation
Intervention / Treatment

-

Contacts and Locations

New Orleans

East Jefferson General Hospital, New Orleans, Louisiana, United States, 70006

New Orleans

Tulane University Medical Center, New Orleans, Louisiana, United States, 70112

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * In this group, patients with AF and OSA who already have done MRI might be included.
  • * History of chronic heart failure (LVEF \< 50%), AF, myocardial infarction, valvular disease.
  • * Prior cardiac or chest surgery.
  • * Other advanced pulmonary disease (severe Chronic Obstructive Pulmonary Disease (COPD) or asthma, pulmonary hypertension) or central sleep apnea.
  • * Contraindications to DE-MRI (e.g. allergy to gadolinium, pacemakers, defibrillators (ICD's), other devices/implants contraindicated for MRI, glomerular filtration rate \<30 ml/min, etc.).
  • * Pregnancy.
  • * Inability to give informed consent.

Ages Eligible for Study

18 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Tulane University,

Amitabh Pandey, MD, PRINCIPAL_INVESTIGATOR, Tulane University Medical Center

Study Record Dates

2025-12