RECRUITING

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence of atrial fibrosis on Delayed Enhancement Magnetic Resonance Imaging (DE-MRI) in OSA patients without atrial fibrillation (AF).

Official Title

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

Quick Facts

Study Start:2021-07-12
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04814420

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * In this group, patients with AF and OSA who already have done MRI might be included.
  1. * History of chronic heart failure (LVEF \< 50%), AF, myocardial infarction, valvular disease.
  2. * Prior cardiac or chest surgery.
  3. * Other advanced pulmonary disease (severe Chronic Obstructive Pulmonary Disease (COPD) or asthma, pulmonary hypertension) or central sleep apnea.
  4. * Contraindications to DE-MRI (e.g. allergy to gadolinium, pacemakers, defibrillators (ICD's), other devices/implants contraindicated for MRI, glomerular filtration rate \<30 ml/min, etc.).
  5. * Pregnancy.
  6. * Inability to give informed consent.

Contacts and Locations

Study Contact

Quintrele Jones, MPH
CONTACT
504-988-3063
qjones1@tulane.edu
Chris Wang, MS
CONTACT
504-988-3065
hwang37@tulane.edu

Principal Investigator

Amitabh Pandey, MD
PRINCIPAL_INVESTIGATOR
Tulane University Medical Center

Study Locations (Sites)

East Jefferson General Hospital
New Orleans, Louisiana, 70006
United States
Tulane University Medical Center
New Orleans, Louisiana, 70112
United States

Collaborators and Investigators

Sponsor: Tulane University

  • Amitabh Pandey, MD, PRINCIPAL_INVESTIGATOR, Tulane University Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-07-12
Study Completion Date2025-12

Study Record Updates

Study Start Date2021-07-12
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Ablation
  • Atrial Fibrosis
  • Delayed Enhancement Magnetic Resonance Imaging
  • Electrocardiogram

Additional Relevant MeSH Terms

  • Atrial Fibrillation
  • Obstructive Sleep Apnea