RECRUITING

Breast Elasticity Imaging During Neoadjuvant Chemotherapy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

For this study, the investigators propose investigation of a new imaging technique, Harmonic Motion Imaging (HMI), and the evaluation of its potential role in prediction of breast cancer response to neoadjuvant chemotherapy (NACT). The investigators hypothesize that changes in HMI parameters will predict response to neoadjuvant systemic therapy in early-stage breast cancer.

Official Title

Predicting Response to Neoadjuvant Chemotherapy Using Harmonic Motion Imaging in Women With Breast Cancer

Quick Facts

Study Start:2021-06-14
Study Completion:2026-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04824027

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Women age ≥18
  2. * Deemed eligible to receive neoadjuvant systemic therapy as per the treating physician, with the dose and schedule deemed appropriate by the treating physician.
  3. * Any stage invasive breast cancer provided the primary breast tumor size is ≥ 4 mm
  1. * Patient is pregnant or lactating
  2. * Presence of breast implants
  3. * History of laser or radiation therapy to the affected breast

Contacts and Locations

Study Contact

Elisa Konofagou, PhD
CONTACT
212-342-1612
ek2191@columbia.edu
Yangpei Liu, MSc
CONTACT
212-342-1612
yl4786@columbia.edu

Principal Investigator

Elisa Konofagou, PhD
PRINCIPAL_INVESTIGATOR
Columbia University

Study Locations (Sites)

Columbia University Irving Medical Center/NYP
New York, New York, 10032
United States

Collaborators and Investigators

Sponsor: Columbia University

  • Elisa Konofagou, PhD, PRINCIPAL_INVESTIGATOR, Columbia University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-06-14
Study Completion Date2026-05

Study Record Updates

Study Start Date2021-06-14
Study Completion Date2026-05

Terms related to this study

Keywords Provided by Researchers

  • Breast cancer
  • Neoadjuvant chemotherapy
  • Harmonic Motion Imaging (HMI)
  • Ultrasound

Additional Relevant MeSH Terms

  • Breast Cancer