RECRUITING

Wells and Enteric Disease Transmission

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Approximately 40 million people in the US are served by private, and frequently untreated, wells. Our best estimate is that 1.3 million cases of gastrointestinal illnesses (GI) per year are attributed to consuming water from untreated private wells in the US, but in reality, there are no robust epidemiological data that can be used to estimate cases of GI attributable to these sources. We propose the first randomized controlled trial (RCT) to estimate the burden of GI associated with private well water. We will test if household treatment of private well water by ultraviolet light (UV) vs. sham (inactive UV device) decreases the incidence of GI in children under 5. We will also examine the presence of viral, bacterial, and protozoan pathogens in stool and well water from participants. These data will fill a knowledge gap on sporadic GI associated with federally-unregulated private water supplies in the US.

Official Title

Wells and Enteric Disease Transmission - A Randomized Trial of Children Supplied Drinking Water From Private Wells (WET-Trial)

Quick Facts

Study Start:2021-07-01
Study Completion:2025-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04826991

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:6 Months to 59 Months
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Child resides in Berks, Bucks, Carbon, Chester, Dauphin, Delaware, Lancaster, Lebanon, Lehigh, Northampton, Montgomery, Monroe, Pike and Schuylkill County in Pennsylvania
  2. * Household is served by a private well
  3. * Participant child is under the age of 5 (under 4 at time of enrollment), who is a full-time resident of the home and drinks untreated well water
  4. * Parent/guardian has access to a phone with texting capabilities
  1. * Child participant is immunocompromised
  2. * Child participant has a chronic gastrointestinal condition
  3. * Child takes daily oral steroids
  4. * Household treats water for microbiological contamination before consumption
  5. * Child exclusively drinks bottled water

Contacts and Locations

Study Contact

Heather M Murphy, PhD
CONTACT
(215)204-5124
heather.murphy@temple.edu

Principal Investigator

Heather M Murphy, PhD
PRINCIPAL_INVESTIGATOR
Temple University

Study Locations (Sites)

Temple University
Philadelphia, Pennsylvania, 19122
United States

Collaborators and Investigators

Sponsor: Temple University

  • Heather M Murphy, PhD, PRINCIPAL_INVESTIGATOR, Temple University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-07-01
Study Completion Date2025-05-31

Study Record Updates

Study Start Date2021-07-01
Study Completion Date2025-05-31

Terms related to this study

Keywords Provided by Researchers

  • drinking water
  • private wells
  • UV disinfection

Additional Relevant MeSH Terms

  • Diarrhea
  • Gastrointestinal Infection
  • Respiratory Viral Infection
  • Waterborne Diseases