The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

Description

the purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.

Conditions

Healthy

Study Overview

Study Details

Study overview

the purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.

The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Norman

Department of Health and Exercise Science, Norman, Oklahoma, United States, 73019

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Healthy men and women
  • * Women must be premenopausal with a regular menstrual cycle (26-30 days)
  • * History of autonomic dysfunction
  • * Cardiovascular diseases
  • * Diabetes
  • * Tobacco/nicotine use
  • * Systolic Pressure \>= 130 mmHg
  • * Diastolic Pressure \>= 85 mmHg
  • * Regular melatonin use \>= 1 use/week
  • * Allergy to melatonin
  • * Cardiometabolic medication use (e.g. anti-hypertensives, insulin-sensitizing, statins)
  • * Sex hormone replacement medical use (e.g. testosterone, estrogen, progesterone)
  • * Pregnancy

Ages Eligible for Study

18 Years to 35 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Oklahoma,

Jeremy M Kellawan, PRINCIPAL_INVESTIGATOR, University of Oklahoma

Study Record Dates

2026-12