Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

Description

This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.

Conditions

Pain, Virtual Reality, Placebo, Temporomandibular Disorder

Talk to us

Study Overview

On this page

Study Details

Study overview

This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

Condition
Pain
Intervention / Treatment

-

Contacts and Locations

Baltimore

Luana Colloca, Baltimore, Maryland, United States, 21201-1512

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age (18-88 years)
  • * English speaker (written and spoken)
  • * Temporal Mandibular Disorder (TMD) for at least 3 months
  • * Present or past degenerative neuromuscular disease
  • * Cardiovascular, neurological diseases, pulmonary abnormalities, kidney disease, liver disease, history of cancer within past 3 years
  • * Cervical pain other than TMD related (e.g. stenosis, radiculopathy)
  • * Any personal (or family first degree) history of mania, schizophrenia, or other psychoses
  • * Severe psychiatric condition (e.g., schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years.
  • * Use of antidepressants, ADHD medication, non-over-the-counter painkillers, methadone, benzodiazepines, barbiturates, and/or narcotics during the past 3 months
  • * Lifetime alcohol/drug dependence or alcohol/drug abuse in the past 3 months
  • * Pregnancy or breastfeeding
  • * Color-blindness
  • * Pain in jaw or temple in last 3 months due to toothache or infection
  • * Any facial trauma that has occurred in the last 6 weeks
  • * History of severe facial trauma in the last 3 months
  • * Impaired or uncorrected hearing
  • * Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection)
  • * Known history of severe motion sickness
  • * High blood pressure or symptomatic low blood pressure
  • * History of fainting
  • * History of angioedema
  • * Failed drug test (testing for opiates, cocaine, methamphetamines, amphetamines, and THC)

Ages Eligible for Study

18 Years to 88 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Maryland, Baltimore,

Luana Colloca, MD/PhD/MS, PRINCIPAL_INVESTIGATOR, University of Maryland Baltimore School of Nursing

Study Record Dates

2027-11-30