RECRUITING

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The TRUST study is a randomized, controlled multicenter study to evaluate the management of gout by comparing two commonly used treatment strategies for gout (TTT vs TTASx) to determine the most beneficial for a patient-centered gout outcomes, as well as relevant cardiovascular-metabolic-renal endpoints.

Official Title

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout: a Randomized Controlled Trial

Quick Facts

Study Start:2024-02-22
Study Completion:2028-10-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04875702

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Ana D Fernandes, MA
CONTACT
617-643-2140
adfernandes@mgh.harvard.edu

Principal Investigator

Hyon K Choi, MD, PhD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

The University of Alabama at Birmingham
South Birmingham, Alabama, 35233
United States
UCLA Health
Santa Monica, California, 90404
United States
Massachusetts General Hospital
Boston, Massachusetts, 02114
United States
Brigham and Women's Hospital (BWH)
Boston, Massachusetts, 02115
United States
Boston Medical Center (BMC)
Boston, Massachusetts, 02119
United States
NYU Langone
NY, New York, 10010
United States
West Virginia University (Including Mobile Clinical Trials Unit)
Morgantown, West Virginia, 26506
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Hyon K Choi, MD, PhD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-02-22
Study Completion Date2028-10-31

Study Record Updates

Study Start Date2024-02-22
Study Completion Date2028-10-31

Terms related to this study

Additional Relevant MeSH Terms

  • Gout