Neurofeedback Intervention for Reading Deficits in Subacute Stroke

Description

The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel brain imaging technique, called real-time functional magnetic resonance imaging (fMRI) neurofeedback combined with right hand motor imagery, this project will re-instate brain activity in the left language-dominant hemisphere. Stroke patients will practice modulating their own brain activity using fMRI neurofeedback signal and will select the most effective mental strategies that help them maintain brain activation patterns associated with better reading recovery.

Conditions

Stroke, Dyslexia, Acquired

Study Overview

Study Details

Study overview

The overall goal of this project is to advance a biologically-based approach to treatment of reading disorders after stroke, which will expand the limits of cognitive rehabilitation. Using a novel brain imaging technique, called real-time functional magnetic resonance imaging (fMRI) neurofeedback combined with right hand motor imagery, this project will re-instate brain activity in the left language-dominant hemisphere. Stroke patients will practice modulating their own brain activity using fMRI neurofeedback signal and will select the most effective mental strategies that help them maintain brain activation patterns associated with better reading recovery.

Rehabilitation of Reading Deficits in Subacute Stroke Using Functional Magnetic Resonance Imaging (fMRI) Neurofeedback and Motor Imagery

Neurofeedback Intervention for Reading Deficits in Subacute Stroke

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

West Orange

Kessler Foundation, West Orange, New Jersey, United States, 07052

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * First-ever left-hemisphere stroke \< 3 months prior to study recruitment or healthy volunteer
  • * Age: 18 - 80 years old
  • * Fluent and literate in English prior to stroke
  • * Reading deficits, defined as \>3 errors on the Paragraphs test (subtests VIII, IX) of the Reading Comprehension Battery for Aphasia-2nd ed. (RCBA-2) in keeping with the healthy control accuracy criterion of 86-100% correct.
  • * Inability to consent or complete study tasks
  • * Inability to undergo MRI (e.g., pregnancy, non-MRI compatible implants, claustrophobia)
  • * A history of prior neurological disease (e.g., brain tumor, Alzheimer's disease)

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Kessler Foundation,

Study Record Dates

2026-06-30