RECRUITING

Overture Metabolomics Non-Selection Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In this study, study investigators will collect embryo culture media on day 5 of vitro fertilization (IVF) culture, prior to vitrification and embryo transfer for testing via Metabolomic screening. Metabolomics is a new, non-invasive method of embryo selection which involves testing discarded embryo culture media for analytes secreted by the developing embryo. These analytes can be used to determine the implantation potential, and ploidy, of the embryo. This study will take place at multiple locations in the United States and Spain.

Official Title

Non-Selection Trial Comparing Metabolomics to Morphology Embryo Selection

Quick Facts

Study Start:2021-05-05
Study Completion:2024-01-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04878991

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Women of any age, including egg donors. 50% will be \<35 and the rest 35 and older.
  2. * Signed Subject Consent Form. No inferior limit on number of eggs
  1. * Require or request PGT of any kind
  2. * Low ovarian reserve defined as follicle stimulating hormone (FSH) \>10 IU/L on day 2-4 of a prior menstrual cycle and anti-mullerian hormone (AMH) \<15 pmol/L (or \<2 ng/ml) within prior 12 months of cycle start

Contacts and Locations

Study Contact

Beatriz Maroto
CONTACT
620521878
beatriz@overture.life
Sara Cabello
CONTACT
sara@overture.life

Principal Investigator

Jose Horcajadas, PhD
PRINCIPAL_INVESTIGATOR
Overture Life
Santiago Munne, PhD
PRINCIPAL_INVESTIGATOR
Overture Life

Study Locations (Sites)

New Hope Fertility Center
New York, New York, 10019
United States

Collaborators and Investigators

Sponsor: Overture Life

  • Jose Horcajadas, PhD, PRINCIPAL_INVESTIGATOR, Overture Life
  • Santiago Munne, PhD, PRINCIPAL_INVESTIGATOR, Overture Life

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-05-05
Study Completion Date2024-01-30

Study Record Updates

Study Start Date2021-05-05
Study Completion Date2024-01-30

Terms related to this study

Keywords Provided by Researchers

  • IVF
  • genetic screening
  • preimplantation genetic testing

Additional Relevant MeSH Terms

  • Infertility