Overture Metabolomics Non-Selection Study

Description

In this study, study investigators will collect embryo culture media on day 5 of vitro fertilization (IVF) culture, prior to vitrification and embryo transfer for testing via Metabolomic screening. Metabolomics is a new, non-invasive method of embryo selection which involves testing discarded embryo culture media for analytes secreted by the developing embryo. These analytes can be used to determine the implantation potential, and ploidy, of the embryo. This study will take place at multiple locations in the United States and Spain.

Conditions

Infertility

Talk to us

Study Overview

On this page

Study Details

Study overview

In this study, study investigators will collect embryo culture media on day 5 of vitro fertilization (IVF) culture, prior to vitrification and embryo transfer for testing via Metabolomic screening. Metabolomics is a new, non-invasive method of embryo selection which involves testing discarded embryo culture media for analytes secreted by the developing embryo. These analytes can be used to determine the implantation potential, and ploidy, of the embryo. This study will take place at multiple locations in the United States and Spain.

Non-Selection Trial Comparing Metabolomics to Morphology Embryo Selection

Overture Metabolomics Non-Selection Study

Condition
Infertility
Intervention / Treatment

-

Contacts and Locations

New York

New Hope Fertility Center, New York, New York, United States, 10019

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Women of any age, including egg donors. 50% will be \<35 and the rest 35 and older.
  • * Signed Subject Consent Form. No inferior limit on number of eggs
  • * Require or request PGT of any kind
  • * Low ovarian reserve defined as follicle stimulating hormone (FSH) \>10 IU/L on day 2-4 of a prior menstrual cycle and anti-mullerian hormone (AMH) \<15 pmol/L (or \<2 ng/ml) within prior 12 months of cycle start

Ages Eligible for Study

18 Years to 50 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Overture Life,

Jose Horcajadas, PhD, PRINCIPAL_INVESTIGATOR, Overture Life

Santiago Munne, PhD, PRINCIPAL_INVESTIGATOR, Overture Life

Study Record Dates

2024-01-30