REDUCE Trial- Reducing Prolapse Recurrence

Description

This study will examine whether surgeons should add a prophylactic posterior colpoperineorrhaphy to a mesh-augmented apical prolapse repair.

Conditions

Prolapse; Female

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Study Overview

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Study Details

Study overview

This study will examine whether surgeons should add a prophylactic posterior colpoperineorrhaphy to a mesh-augmented apical prolapse repair.

REDUCE Trial - Reducing Prolapse Recurrence by Reducing the Genital Hiatus

REDUCE Trial- Reducing Prolapse Recurrence

Condition
Prolapse; Female
Intervention / Treatment

-

Contacts and Locations

Chicago

Northwestern University, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Women over the age of 18
  • * English or Spanish speaking
  • * Symptomatic prolapse (stage II or greater) undergoing minimally-invasive sacrocolpopexy with Restorelle ultra lightweight mesh
  • * Preoperative genital hiatus with valsalva/strain greater than or equal to 4cm
  • * Patient has had prior prolapse surgery
  • * Patient has inflammatory bowel disease (Crohn's, Ulcerative Colitis)
  • * Baseline dyspareunia (patient reports that they have pain with vaginal intercourse when asked as a yes/no)
  • * Patients with a score of 7 or greater in any one muscle on the Meister Pelvic Floor Exam
  • * Patient planning a concomitant Burch procedure
  • * Pregnant

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Northwestern University,

Julia Geynisman-Tan, M.D, PRINCIPAL_INVESTIGATOR, Northwestern University

Study Record Dates

2026-07-30