RECRUITING

Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

PrevisEA is a noninvasive, disposable device that uses audio spectral analysis of sounds produced by the gastrointestinal tract to predict gastrointestinal impairment (GII). GII is most commonly associated with postoperative ileus (POI), but could be the result of other causes, such as early postoperative bowel obstruction. GII is defined as failure of successful early oral re-feeding in a subject undergoing major abdominal surgery. For subjects who are allowed to resume a diet during the first 24 hours after surgery, a failure to successfully orally re-feed a subject is defined as presentation with emesis, requiring a reversal of diet, or the placement of a nasogastric tube on first postoperative day or later. The device is considered non-significant risk (NSR). The device does not inform medical decisions in this study. Researchers will be blinded to results of the device during this study.

Official Title

A Minimal-Risk, Multi-Center, Prospective, Clinical Trial to Evaluate the PrevisEA Device for Predicting Gastrointestinal Impairment

Quick Facts

Study Start:2021-09-14
Study Completion:2024-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04880473

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age ≥ 18 and ≤ 90 years
  2. 2. Patient undergoing elective intestinal resection surgery including open, laparoscopic, robotic, or hand-assist technique for:
  3. 1. Segmental ileocolic resection with or without diversion
  4. 2. Segmental colon resection with or without diversion
  5. 3. Segmental coloproctectomy with or without diversion
  6. 4. Low anterior resection with or without diversion
  7. 5. Abdominoperineal resection
  8. 6. Total abdominal colectomy with or without diversion
  9. 7. Proctocolectomy with or without end ileostomy or diversion
  10. 8. Closure of end colostomy (Hartmann's reversal)
  1. 1. Allergies to any of the device components (i.e., adhesive)
  2. 2. Inability to have prototype device applied to their abdominal wall due to disease conditions or surgical alterations(e.g., fistulas, stomas, drains, etc.)
  3. 3. Patients undergoing:
  4. 1. Small bowel resection without colonic resection
  5. 2. Transanal proctectomy without transabdominal approach
  6. 3. Perineal proctosigmoidectomy
  7. 4. Closure of loop colostomy or ileostomy
  8. 4. Patients with preoperative evidence of an anastomotic leak, deep wound infection, organ space infection, or urinary tract infection

Contacts and Locations

Study Contact

Entac Medical Inc.
CONTACT
845-773-8473
previsea-001@clinicalresearchstrategies.com

Study Locations (Sites)

Adventist Health System/Sunbelt, Inc. d/b/a AdventHealth Orlando
Orlando, Florida, 32803
United States
Northwestern University
Chicago, Illinois, 60611
United States
Spectrum Health Blodgett Hospital
Grand Rapids, Michigan, 49503
United States
University of Minnesota
Minneapolis, Minnesota, 55414
United States
Mayo Clinic
Rochester, Minnesota, 55905
United States
The University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599-1350
United States
The Cleveland Clinic Foundation
Cleveland, Ohio, 44195
United States
Oregon Health and Science University
Portland, Oregon, 97239
United States

Collaborators and Investigators

Sponsor: Entac Medical Inc.

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-14
Study Completion Date2024-12-01

Study Record Updates

Study Start Date2021-09-14
Study Completion Date2024-12-01

Terms related to this study

Keywords Provided by Researchers

  • Postoperative ileus
  • Postoperative bowel obstruction
  • Emesis
  • Reversal of diet
  • Nasogastric tube
  • Abdominal sounds
  • Gastrointestinal impairment
  • Elective intestinal resection

Additional Relevant MeSH Terms

  • Gastrointestinal Complication