Time-Restricted Feeding Intervention in Metabolically-Unhealthy Postmenopausal Women

Description

This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms and the associated metabolic dysfunction. It is hypothesized that time-restricted feeding will improve insulin sensitivity, glucose tolerance, body weight, and other metabolic parameters in metabolically-unhealthy postmenopausal women.

Conditions

Metabolic Syndrome, Postmenopausal Symptoms

Study Overview

Study Details

Study overview

This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms and the associated metabolic dysfunction. It is hypothesized that time-restricted feeding will improve insulin sensitivity, glucose tolerance, body weight, and other metabolic parameters in metabolically-unhealthy postmenopausal women.

Time-Restricted Feeding Intervention in Metabolically-Unhealthy Postmenopausal Women

Time-Restricted Feeding Intervention in Metabolically-Unhealthy Postmenopausal Women

Condition
Metabolic Syndrome
Intervention / Treatment

-

Contacts and Locations

Lexington

University of Kentucky, Lexington, Kentucky, United States, 40536

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * postmenopausal women
  • * age 45-65 years
  • * prediabetic or have at least 2 features of metabolic syndrome
  • * on hormone therapy
  • * diabetes
  • * heart disease
  • * alcohol consumption of \>2 drinks per day
  • * significant circadian disruption
  • * having care-taking responsibilities that significantly affect sleep
  • * shift work or irregular lifestyle
  • * uncontrolled sleep apnea or other uncontrolled sleep disorder
  • * extreme early or late chronotypes
  • * significant psychiatric disorders
  • * taking ADHD medications
  • * diagnosed dysregulated eating behaviors
  • * smoking \>5 cigarettes/day or 30 pack-year history
  • * participating in formal weight loss program
  • * not weight stable

Ages Eligible for Study

45 Years to 65 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Julie Pendergast,

Julie S Pendergast, PhD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

2027-01-31