Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

Description

The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients with subacute stroke.

Conditions

Ischemic Stroke, Cognitive Impairment

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Study Overview

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Study Details

Study overview

The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients with subacute stroke.

Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke (TRAINS): Neuromodulatory Intervention to Ameliorate Cognition After Stroke for Individuals At Risk for VCID.

Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

Condition
Ischemic Stroke
Intervention / Treatment

-

Contacts and Locations

Philadelphia

Penn Medicine Rehabilitation, Philadelphia, Pennsylvania, United States, 19146

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Stroke that occurred within 4 weeks of the study
  • * Presence of cognitive impairment attributable to stroke
  • * Between the ages of 18 and 90
  • * Able to understand the nature of the study and give informed consent
  • * Able to follow simple commands as evidenced by NIHSS subtest 1C =0
  • * History of chronic, serious, or unstable neurologic illness other than stroke
  • * Current unstable medical illness(es)
  • * History of reoccurring seizures or epilepsy
  • * Current abuse of alcohol or drugs (prescription or otherwise)
  • * Active and severe psychiatric disorder
  • * Metallic objects in the face or head other than dental apparatus such as braces, fillings, and implants.
  • * Pregnancy

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pennsylvania,

Kelly Sloane, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Roy Hamilton, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

2027-01