RECRUITING

Patient-centered, Optimal Integration of Survivorship and Palliative Care

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to develop and test the feasibility of a supportive care model (POISE) for patients with metastatic Non-small Cell Lung Cancer (NSCLC). The main questions are * is POISE feasible to deliver and acceptable to patients * what is the effect of POISE on the distress patients feel related to their uncertain future, their confidence in their ability to manage cancer, and their understanding about what to expect Participants in the randomized controlled trial will receive either the new supportive care model, POISE, which consists of four visits with a trained palliative care clinician, or care as usual, and will be asked to complete three surveys.

Official Title

Patient-centered, Optimal Integration of Survivorship and Palliative Care

Quick Facts

Study Start:2023-09-29
Study Completion:2027-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04900935

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 or older
  2. * MGH Cancer Center patient
  3. * Within 6 months of diagnosis of metastatic NSCLC with oncogenic driver mutation (EGFR, ALK, ROS1, RET)
  4. * Receiving targeted therapy
  5. * Ability to respond in English or Spanish
  1. * Cognitive impairment or serious mental illness that limits ability to provide informed consent
  2. * Need for urgent palliative care or hospice referral
  3. * Pregnant women
  4. * Prisoners

Contacts and Locations

Study Contact

Laura A Petrillo, MD
CONTACT
(617) 724-4000
lpetrillo2@mgh.harvard.edu

Principal Investigator

Laura A Petrillo, MD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Laura A Petrillo, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-29
Study Completion Date2027-09-01

Study Record Updates

Study Start Date2023-09-29
Study Completion Date2027-09-01

Terms related to this study

Keywords Provided by Researchers

  • Stage IV Non-small Cell Lung Cancer
  • Targeted Therapy
  • Nonsmall Cell Lung Cancer
  • Carcinoma, Non-Small-Cell Lung
  • ALK-positive Non-small Cell Lung Cancer
  • EGFR Positive Non-small Cell Lung Cancer
  • ROS1 Positive Non-Small Cell Lung Cancer
  • Palliative care
  • survivorship
  • RET Fusion positive Non-Small Cell Lung Cancer

Additional Relevant MeSH Terms

  • Stage IV Non-small Cell Lung Cancer
  • Targeted Therapy
  • Nonsmall Cell Lung Cancer
  • Carcinoma, Non-Small-Cell Lung
  • ALK-positive Non-small Cell Lung Cancer
  • EGFR Positive Non-small Cell Lung Cancer
  • Palliative Care
  • Survivorship