Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole

Description

This study aims to compare two FDA approved medications (aripiprazole and risperidone) for the treatment of behavioral dysregulation in children with autism spectrum disorders. This trial, done in the context of routine clinical care, will seek to evaluate whether aripiprazole or risperidone is associated with more weight gain in children.

Conditions

Weight Gain, Autism Spectrum Disorder, Medication Side Effect

Study Overview

Study Details

Study overview

This study aims to compare two FDA approved medications (aripiprazole and risperidone) for the treatment of behavioral dysregulation in children with autism spectrum disorders. This trial, done in the context of routine clinical care, will seek to evaluate whether aripiprazole or risperidone is associated with more weight gain in children.

Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole

Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole

Condition
Weight Gain
Intervention / Treatment

-

Contacts and Locations

Nashville

Division of Developmental Medicine, Nashville, Tennessee, United States, 37212

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * age 17 years and younger
  • * diagnosed with autism
  • * have behavior problems
  • * seen in Vanderbilt clinic
  • * naïve to atypical antipsychotics
  • * 18 years or older
  • * history of atypical antipsychotic use
  • * not diagnosed with autism

Ages Eligible for Study

to 17 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Vanderbilt University Medical Center,

Angela Maxwell-Horn, M.D., PRINCIPAL_INVESTIGATOR, Vanderbilt University Medical Center

Study Record Dates

2025-07-01