Xeomin® and Gait Related Mobility After Stroke

Description

The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patients before and 4-6-weeks after Xeomin® injection into the upper limb, using two standardized tests of physical function in outpatient rehabilitation that are widely used; the 10-meter walk test and the timed 'up and go' test (TUG).

Conditions

Stroke

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Study Overview

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Study Details

Study overview

The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patients before and 4-6-weeks after Xeomin® injection into the upper limb, using two standardized tests of physical function in outpatient rehabilitation that are widely used; the 10-meter walk test and the timed 'up and go' test (TUG).

Upper Extremity Injection of Xeomin® and Changes in Gait Related Mobility in Adults After Stroke

Xeomin® and Gait Related Mobility After Stroke

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Charlotte

Carolinas Rehabilitation, Charlotte, North Carolina, United States, 28203

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of hemiparesis and spasticity secondary to stroke with upper and lower limb spasticity and unilateral motor and/or sensory deficit
  • * No prior surgery to the lower limb
  • * Able to walk at least 10 meters without physical assistance from another person and without an assistive device
  • * Toe- ground clearance during swing phase without assistive device or orthoses
  • * No treatment with botulinum toxin within the past 4 months
  • * Passive range of motion at either the ankle, knee, or elbow joint less than 30 degrees
  • * Participants with uncorrected hearing impairment
  • * Weight bearing restrictions due to concurrent orthopedic injuries that would make ambulating with or without an assistive device unsafe
  • * Speech language expression deficit (e.g., aphasia)
  • * Absence of proprioception upon neurologic examination
  • * Presence of fixed contractures in the upper or lower extremities not correctable to neutral
  • * Other confounding neurological diagnoses or active acute illness (cancer, Parkinson's disease, multiple sclerosis)

Ages Eligible for Study

18 Years to 79 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Wake Forest University Health Sciences,

Mark A Hirsch, PhD, PRINCIPAL_INVESTIGATOR, Wake Forest University Health Sciences

Study Record Dates

2026-04