RECRUITING

In Vivo Study of THC-induced Immune-genome Changes at Single Cell Solution in HIV-infected Humans

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In this study, the investigators hypothesize that THC alters the immunogenome in a cell type-specific fashion and alters cytokine production via epigenetic regulatory mechanisms and that these alterations differ between HIV-infected and HIV-uninfected host genomes.

Official Title

In Vivo Study of THC-induced Immune-genome Changes at Single Cell Solution in HIV-infected Humans

Quick Facts

Study Start:2022-02-08
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04920539

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Brooklyn A Bradley, BS
CONTACT
203-932-5711
bb889@yale.edu
Heather R Garrett, BS
CONTACT
203-932-5711
heather.garrett@yale.edu

Principal Investigator

Deepak C D'Souza, MD
PRINCIPAL_INVESTIGATOR
Yale University Professor of Psychiatry

Study Locations (Sites)

VA Connecticut Healthcare System
West Haven, Connecticut, 06516
United States

Collaborators and Investigators

Sponsor: Yale University

  • Deepak C D'Souza, MD, PRINCIPAL_INVESTIGATOR, Yale University Professor of Psychiatry

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-02-08
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2022-02-08
Study Completion Date2025-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • HIV Infections
  • Healthy