Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function

Description

Older adults with coronary artery disease (CAD) have impaired vascular and inspiratory muscle function. The objective of this study is to examine the effect of beet juice supplementation on vascular and inspiratory muscle function in older adults with CAD.

Conditions

Coronary Artery Disease

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Study Overview

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Study Details

Study overview

Older adults with coronary artery disease (CAD) have impaired vascular and inspiratory muscle function. The objective of this study is to examine the effect of beet juice supplementation on vascular and inspiratory muscle function in older adults with CAD.

Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function

Effect of Beet Juice Supplementation on Vascular and Inspiratory Muscle Function

Condition
Coronary Artery Disease
Intervention / Treatment

-

Contacts and Locations

Gainesville

Integrative Cardiovascular Physiology Laboratory, University of Florida, Gainesville, Florida, United States, 32611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adults with coronary artery disease (CAD) based on an angiogram \>50% stenosis in any major epicardial vessel or history of myocardial infarction or history of coronary revascularization.
  • * Considered to have stable CAD on optimal medical therapy
  • * 60 to 85 years of age
  • * Men and women (women must be postmenopausal either natural or surgical)
  • * Able to give consent
  • * Ejection fraction \<50%, unstable angina, recent myocardial infarction within 6 months
  • * Coronary revascularization, including percutaneous coronary intervention and coronary artery bypass graft or thoracic surgery within 6 months.
  • * Stroke, obstructive pulmonary disease, hepatitis B, C, HIV, seizures, or other relevant on-going or recurrent illness
  • * Individuals that have participated in respiratory training within the last 12 months or cardiac rehabilitation within the last 6 months
  • * Uncontrolled hypertension
  • * Use of tobacco products including smoking traditional or e-cigarettes
  • * Use of hormone replacement therapy in women or men (e.g., estrogen, progesterone or testosterone)
  • * Regular aerobic exercise training
  • * Unwilling to stop using mouthwash at least 1 week before the start of the study and during study participation
  • * Unwilling to remain weight stable during study participation

Ages Eligible for Study

60 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Florida,

Study Record Dates

2025-08-30