The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis

Eligibility Criteria

• * Age between 25 and 75 years-old
• * Diagnosis of pre-existing osteoarthritis of the glenohumeral joint
• * Working understanding of the English language and able to fully understand the procedure
• * Capable of providing informed consent
• * Able to complete online, in-person or phone surveys for the purposes of follow-up
• * Capable of understanding pre- and post-procedure care instructions
• * Ambulatory at baseline
• * Previous trial and failure of conservative therapy consisting of a minimum of 6 weeks of physical therapy and trial of anti-inflammatory medications if not contraindicated, with or without concomitant bracing and/or injections.
• * Age \< 25 or \> 75 years old
• * Radiographs demonstrating either no, little osteoarthritis, severe(bone on bone) osteoarthritis
• * Prior total or partial joint replacement surgery or surgery involving cartilage regeneration
• * Previous cortisone, PRP or Hyaluronic acid intra-articular injection within the last 3 months
• * Co-morbidity with the rheumatologic condition, inflammatory arthritis
• * Currently undergoing immunomodulatory therapy
• * Uncontrolled endocrine disorder
• * BMI \>40 or joint space not visible by ultrasound
• * Current diagnosis of osteomyelitis, human immunodeficiency virus (HIV-1, -2) and/or hepatitis C (HCV), infection, and poorly controlled diabetes (HgA1C \>7.0)
• * Pregnancy or planned pregnancy
• * previous stem cell injection into treatment joint
• * Patient scheduled to undergo any concomitant shoulder surgical procedures or other surgery which may affect outcomes.
• * Coagulopathy or anticoagulant treatment
• * Chronic pain involving multiple body parts or opioid medication management
• * Diagnosis of fibromyalgia
• * Concomitant massive(2 tendons with retraction), complete rotator cuff tendon tear