RECRUITING

Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel (Bupivacaine) for the treatment of craniofacial pain. This study would be conducted in a prospective, randomized, double-blinded, placebo- controlled, and cross-over fashion. We aim to investigate whether the administration of Exparel (Bupivacaine) to the lateral nasal wall may positively impact craniofacial pain and functional outcomes, in patients who experience relief with the topical application of Lidocaine (routinely given prior to almost all ENT endoscopy).

Official Title

Prospective, Randomized, Double-blinded, Placebo-controlled, Cross-over Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) Towards the Ipsilateral Pterygopalatine Fossa for the Treatment of Craniofacial Pain

Quick Facts

Study Start:2023-02-01
Study Completion:2030-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04930887

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients with a chief complaint of craniofacial pain (migraine, cluster headache, trigeminal autonomic cephalgia, sphenopalatine ganglioneuraligia, paroxysmal hemicrania) who has Stanford Pain \& ENT clinic visit
  1. * age \<18 or \>80
  2. * pregnant women
  3. * economically disadvantaged (not able to afford clinic visits/treatments)
  4. * decisionally impaired (unable to obtain informed consent)
  5. * has allergy to bupivacaine
  6. * unable or unwilling to participate plans to participate in another clinical study at any time during this study

Contacts and Locations

Study Contact

Peter Hwang, MD
CONTACT
(650) 723-5281
hwangph@stanford.edu

Principal Investigator

Peter Hwang, MD
PRINCIPAL_INVESTIGATOR
Stanford University

Study Locations (Sites)

Peter H Hwang
Stanford, California, 94304
United States

Collaborators and Investigators

Sponsor: Stanford University

  • Peter Hwang, MD, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-02-01
Study Completion Date2030-06

Study Record Updates

Study Start Date2023-02-01
Study Completion Date2030-06

Terms related to this study

Additional Relevant MeSH Terms

  • Craniofacial Pain
  • Migraine
  • Cluster Headache
  • Trigeminal Autonomic Cephalgia
  • Sphenopalatine Ganglion Neuralgia
  • Paroxysmal Hemicrania