RECRUITING

Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Acute pancreatitis is among the most common gastroenterology diagnosis in the United States, and represents a large economic burden to the United States health system. While recent guidelines agree early feeding shortens length of stay, these guidelines fail to provide recommendations on optimal diet to start leaving diet type to clinician discretion. Therefore, the aim is to assess the comparative efficacy of full calorie regular diet (RD) versus clear liquid diet (CLD) on length of hospital stay (LOHS) for mild to moderate acute pancreatitis (AP). The study population will target mild to moderate acute pancreatitis patients who can tolerate eating in a single institution. The primary end point will focus on LOHS, and secondary end points will include Pancreatic Activity Scoring System, side effects and readmission.

Official Title

To Assess the Comparative Efficacy of Full Calorie Regular Diet (RD) Versus Clear Liquid Diet (CLD) on Length of Hospital Stay (LOHS) for Mild to Moderate Acute Pancreatitis (AP)

Quick Facts

Study Start:2021-07-18
Study Completion:2024-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04932785

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. \>18 years of age
  2. 2. Presentation with acute pancreatitis as defined by two of three criterion per the Revised Atlanta Criteria guidelines: (a) Amylase or lipase \> 3x the upper limit of normal, b) Classical abdominal pain, c) Ultrasound or computed tomography of unequivocal pancreatitis. Such radiographic findings include swelling, edema, or heterogeneity of the gland or peripancreatic fluid or stranding
  1. 1. Pregnant or breastfeeding women
  2. 2. Incarcerated patients
  3. 3. Patients \< 18 years of age
  4. 4. Patient unable or unwilling to give informed consent
  5. 5. Patients transferred from another hospital
  6. 6. The possibility of poor oral intake for reasons other than acute pancreatitis (e.g. intubation, failure to pass an indicated swallow study for aspiration risk, anorexia secondary to active malignancy, etc)
  7. 7. Surgical intervention for infected pancreatic necrosis or pancreatic hemorrhage
  8. 8. Chronic pancreatitis based on radiographic evidence
  9. 9. Severe pancreatitis based on Revised Atlanta Criteria. Under Revised Atlanta Criteria, patients will be excluded if they have a composite Modified Marshall \>2
  10. 10. Etiologies of hypertriglyceridemia, trauma and autoimmune pancreatitis will be excluded

Contacts and Locations

Study Contact

Patrick Chang, MD
CONTACT
323-409-5050
patrick.chang@med.usc.edu
Jessica Serna, BS
CONTACT
323-409-6939
jessica.serna@med.usc.edu

Principal Investigator

James Buxbaum, MD
PRINCIPAL_INVESTIGATOR
Principal Investigator

Study Locations (Sites)

LAC+USC Medical Center
Los Angeles, California, 90033
United States

Collaborators and Investigators

Sponsor: University of Southern California

  • James Buxbaum, MD, PRINCIPAL_INVESTIGATOR, Principal Investigator

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-07-18
Study Completion Date2024-07

Study Record Updates

Study Start Date2021-07-18
Study Completion Date2024-07

Terms related to this study

Additional Relevant MeSH Terms

  • Pancreatitis
  • Diet, Food, and Nutrition
  • Diet
  • Pancreatic Disease
  • Enteral Nutrition