RECRUITING

Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of this proposal is to study circulating and echocardiographic markers of pulmonary vascular and right ventricular remodeling in patients with a WHO-2 diagnosis of pulmonary hypertension after mitral valve procedures. The investigators are proposing the study will be impactful for the early detection and prediction and of residual pulmonary hypertension (PH) that would otherwise be undetected and fatal with no curative treatment.

Official Title

Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures

Quick Facts

Study Start:2021-12-21
Study Completion:2025-10-20
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04947384

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * \>= 18 years/old
  1. * Patients with ejection fraction (EF) \< 35%
  2. * Patients with severe tricuspid valve regurgitation
  3. * Transplant patients
  4. * Patients scheduled for ventricular assist devices
  5. * Patients with a diagnosis of heart failure with preserved ejection fraction
  6. * Any aortic valvular disease

Contacts and Locations

Study Contact

Kera Marshall
CONTACT
205-934-4042
keramarshall@uabmc.edu
LaShun Horn, MS
CONTACT
205-996-2606
llhorn@uabmc.edu

Principal Investigator

Ahmed Zaky, MD
PRINCIPAL_INVESTIGATOR
The University of Alabama at Birmingham

Study Locations (Sites)

The University of Alabama at Birmingham
Birmingham, Alabama, 35294
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

  • Ahmed Zaky, MD, PRINCIPAL_INVESTIGATOR, The University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-12-21
Study Completion Date2025-10-20

Study Record Updates

Study Start Date2021-12-21
Study Completion Date2025-10-20

Terms related to this study

Additional Relevant MeSH Terms

  • Pulmonary Hypertension