Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures

Description

The objective of this proposal is to study circulating and echocardiographic markers of pulmonary vascular and right ventricular remodeling in patients with a WHO-2 diagnosis of pulmonary hypertension after mitral valve procedures. The investigators are proposing the study will be impactful for the early detection and prediction and of residual pulmonary hypertension (PH) that would otherwise be undetected and fatal with no curative treatment.

Conditions

Pulmonary Hypertension

Study Overview

Study Details

Study overview

The objective of this proposal is to study circulating and echocardiographic markers of pulmonary vascular and right ventricular remodeling in patients with a WHO-2 diagnosis of pulmonary hypertension after mitral valve procedures. The investigators are proposing the study will be impactful for the early detection and prediction and of residual pulmonary hypertension (PH) that would otherwise be undetected and fatal with no curative treatment.

Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures

Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures

Condition
Pulmonary Hypertension
Intervention / Treatment

-

Contacts and Locations

Birmingham

The University of Alabama at Birmingham, Birmingham, Alabama, United States, 35294

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * \>= 18 years/old
  • * Patients with ejection fraction (EF) \< 35%
  • * Patients with severe tricuspid valve regurgitation
  • * Transplant patients
  • * Patients scheduled for ventricular assist devices
  • * Patients with a diagnosis of heart failure with preserved ejection fraction
  • * Any aortic valvular disease

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Alabama at Birmingham,

Ahmed Zaky, MD, PRINCIPAL_INVESTIGATOR, The University of Alabama at Birmingham

Study Record Dates

2025-10-20