Time Restricted Feeding, Muscle, and Metabolism

Description

Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.

Conditions

Overweight, Obesity

Study Overview

Study Details

Study overview

Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.

Time Restricted Feeding Intervention for Muscle and Metabolic Health (TRIMM)

Time Restricted Feeding, Muscle, and Metabolism

Condition
Overweight
Intervention / Treatment

-

Contacts and Locations

Fayetteville

University of Arkansas, Fayetteville, Arkansas, United States, 72704

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Resides in Northwest Arkansas
  • * Age 25-50 years
  • * BMI \> 25
  • * All ethnicities
  • * Female and male
  • * Food allergies
  • * Pregnant or breastfeeding
  • * Dietary restrictions (e.g. vegetarian, vegan, etc.)
  • * Trying to lose weight in last 3 months
  • * Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension)
  • * Prescription medications related to heart disease or type 2 diabetes
  • * Fear of needles
  • * Smoker or vaping
  • * Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes
  • * Consumes \>4 alcoholic beverages per week

Ages Eligible for Study

25 Years to 50 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Arkansas, Fayetteville,

Study Record Dates

2025-05-30