RECRUITING

Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Background: Brain activity produces magnetic fields. These fields can be measured outside the head. Existing technology, called MEG, measures these fields. Researchers are testing a new type of magnetic field sensor called OPM. They hope it can help pinpoint with very high accuracy where brain activity is generated. Objective: To develop and test a new type of sensor for measuring the magnetic fields produced by brain activity. Eligibility: Healthy people ages 18-65 who had a magnetic resonance imaging (MRI) scan under protocol 17-M-0181. Design: Participants may be asked to complete sessions on both the traditional MEG instrument and the OPM array. For the MEG, 3 small coils will be placed on the participant s face with tape. Their head will be positioned inside the MEG device. For the OPM, sensors are housed in a 3d printed array. The sensors will be attached to a cap placed on the participant s head. For both scans, participants will be seated in a chair inside a magnetically shielded room. They may complete several tasks. In one task, plastic cells will be placed on their fingers. Puffs of air will be sent to these cells, which will stimulate the sense of touch. Other tasks may include the following stimuli: visual (such as checkerboards), auditory (such as beeps and tones), or language (words and letters). Researchers may also obtain recordings while they stimulate the nerve in the participant s forearm using electrical current in small electrodes. Participation is expected to last for 1 day. Additional optional scans may be offered for up to 1 year....

Official Title

Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array

Quick Facts

Study Start:2022-05-12
Study Completion:2025-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04950309

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Provision of signed and dated informed consent form
  2. 2. Stated willingness to comply with all study procedures and availability for the duration of the study
  3. 3. Male or female, aged 18-65
  4. 4. In good general health as evaluated according to protocol 17-M-0181
  5. 5. Completed a magnetic resonance imaging (MRI) scan under 17-M-0181
  1. 1. Participants excluded from 17-M-0181 will be excluded from this protocol
  2. 2. Metal in the body which would cause artifacts on MEG recordings

Contacts and Locations

Study Contact

Anna M Namyst
CONTACT
(301) 402-2445
anna.namyst@nih.gov
Allison Nugent, Ph.D.
CONTACT
(301) 451-8863
nugenta@mail.nih.gov

Principal Investigator

Allison Nugent, Ph.D.
PRINCIPAL_INVESTIGATOR
National Institute of Mental Health (NIMH)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Institute of Mental Health (NIMH)

  • Allison Nugent, Ph.D., PRINCIPAL_INVESTIGATOR, National Institute of Mental Health (NIMH)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-05-12
Study Completion Date2025-08-01

Study Record Updates

Study Start Date2022-05-12
Study Completion Date2025-08-01

Terms related to this study

Keywords Provided by Researchers

  • Imaging
  • biomagnetism
  • somatotopy
  • optically pumped magnetometer
  • Magnetoencephalography

Additional Relevant MeSH Terms

  • Normal Physiology