RECRUITING

Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor called Recombinant Human Platelet-Derived Growth Factor (rhPDGF).

Official Title

Lateral Ridge Augmentation Using Allograft Bone Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor: A Clinical and Histological Randomized Controlled Trial

Quick Facts

Study Start:2021-08-11
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04954664

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * English speaking
  2. * At least 18 years old
  3. * Must be a patient of the UAB Dental School
  4. * Able to read and understand informed consent document
  5. * Need for implants to replace missing tooth or teeth in at least one quadrant of the mouth.
  6. * Insufficient alveolar ridge width for endosseous implant placement defined as 5mm or less as determined by bone sounding and cone beam computed tomography (CBCT) scan.
  1. * Non-English speaking
  2. * Less than 18 years old
  3. * Smokers/tobacco users (\>10 cigarettes/day)
  4. * Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
  5. * Patient is a poor compliance risk (i.e., poor oral hygiene, history of alcohol or drug abuse)
  6. * Vertical loss of bone at edentulous ridge.

Contacts and Locations

Study Contact

Hussein Basma, DDS, MS
CONTACT
205-934-2888
basma86@uab.edu
Sarah Startley, DMD
CONTACT
205-975-8711
ss1971@uab.edu

Study Locations (Sites)

Unversity of Alabama at Birmingham, School of Dentistry
Birmingham, Alabama, 35294-0007
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-08-11
Study Completion Date2025-12

Study Record Updates

Study Start Date2021-08-11
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • New bone
  • Dental implants

Additional Relevant MeSH Terms

  • Dental Implant
  • Bone Loss