RECRUITING

Effect of NMES on Balance and Fall Risk in Chronic Stroke

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The aim of this study is to describe the effect of neuromuscular electrical stimulation (NMES) in the form of functional electrical stimulation (FES) applied to different lower limb muscles on reactive balance and gait performance in stroke participants. Methods: Twenty individuals with chronic stroke will be asked to perform an experimental protocol that includes a postural disturbance in the form of a slip- or trip-like perturbation and a standardized walking test in both laboratory and outdoor environments with and without FES applied to different lower limb muscles of the paretic leg. FES will be applied using an advanced software that is able to synchronize muscle activation with the time of perturbation onset and according to the phases of gait. This project design aims to examine whether a specific pattern of lower limb muscle stimulation could improve the kinematic and behavioral responses during reactive balance following slip- and trip-like perturbations. Additionally, the project aims to see if the kinematic and spatio-temporal gait parameters can be modified during a standardized walking test under different sensory and environmental conditions.

Official Title

Effect of Neuromuscular Electrical Stimulation (NMES) on Reactive Balance, Gait and Fall-risk in Individuals with Stroke

Quick Facts

Study Start:2021-05-15
Study Completion:2025-11-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04957355

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Presence of hemiparesis.
  2. 2. Onset of stroke (\> 6 months).
  3. 3. Ability to walk independently with or without an assistive device for at least 300 ft.
  4. 4. Can understand and communicate in English.
  5. 5. Cognitively and behaviorally capable of complying with the regimen (Montreal Cognitive Assessment \> 25/30).
  1. 1. Body weight more than 250 lbs.
  2. 2. Any neurological condition other than stroke.
  3. 3. Any cardiopulmonary, musculoskeletal, or systemic diagnosis.
  4. 4. Recent major surgery (\< 6 months) or hospitalization (\< 3 months).
  5. 5. Deep venous thrombosis.
  6. 6. Antecedent of cancer.
  7. 7. Peripheral nerve injury or neuropathy in the affected limb with motor disability.
  8. 8. Spasticity (Ashworth scale \> 2).
  9. 9. Uncontrolled high blood pressure/angina.
  10. 10. Skin condition not tolerant with FES therapy.
  11. 11. Uncontrolled seizure disorder.
  12. 12. Botox treatment within the last 5 months.
  13. 13. History of epilepsy.
  14. 14. Pacemaker users.

Contacts and Locations

Study Contact

Rudri M Purohit, MS,PT
CONTACT
3124139772
rpuroh2@uic.edu
Lakshmi Kannan, MS,PT
CONTACT
3124133175
lkanna2@uic.edu

Principal Investigator

Tanvi Bhatt, PhD
PRINCIPAL_INVESTIGATOR
University of Illinois at Chicago

Study Locations (Sites)

University of Illinois at Chicago
Chicago, Illinois, 60612
United States

Collaborators and Investigators

Sponsor: University of Illinois at Chicago

  • Tanvi Bhatt, PhD, PRINCIPAL_INVESTIGATOR, University of Illinois at Chicago

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-05-15
Study Completion Date2025-11-30

Study Record Updates

Study Start Date2021-05-15
Study Completion Date2025-11-30

Terms related to this study

Keywords Provided by Researchers

  • functional electrical stimulation
  • neuromuscular electrical stimulation
  • walk-training
  • treadmill training
  • reactive balance
  • perturbation
  • falls
  • fall prevention

Additional Relevant MeSH Terms

  • Chronic Stroke