RECRUITING

The Accuracy of Amniotic Fluid Ferning in the Second Trimester in the Diagnosis of Preterm Prelabor Rupture of Membranes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Although much investigation has been done on the use of ferning in the second and third trimesters, particularly with the development of rapid protein clinical assays, there appears to be lower ferning rates in clinical practice with traditional techniques compared to previous published research on the subject. Much of the older study designs are lacking in detail and lack a large enough sample sizes at each gestational age to appropriately interpret the significance of ferning results by gestational age. Additionally, a large premise for the current tests used to diagnose rupture of membranes is based on these older studies. Given this, we propose collecting amniotic fluid vaginally to evaluate for the presence of ferning in the second trimester to determine if there is a difference in ferning based on gestational age as well as the time interval after rupture of membranes in which ferning can observed on microscope examination.

Official Title

Assessing the Accuracy of Amniotic Fluid Ferning in the Second Trimester in the Diagnosis of Preterm Prelabor Rupture of Membranes

Quick Facts

Study Start:2021-09-17
Study Completion:2023-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04963465

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years or older
  2. * English speaking
  3. * singleton or multi fetal gestation
  4. * between 15 and 24 weeks gestation
  5. * undergoing elective pregnancy termination
  1. * known rupture of membranes or anhydramnios

Contacts and Locations

Study Contact

OBGYN Research Director
CONTACT
518-262-4942
Obgynresearch@amc.edu

Principal Investigator

OBGYN Research Director
PRINCIPAL_INVESTIGATOR
Albany Medical College

Study Locations (Sites)

Albany Medical Center
Albany, New York, 12208
United States

Collaborators and Investigators

Sponsor: Albany Medical College

  • OBGYN Research Director, PRINCIPAL_INVESTIGATOR, Albany Medical College

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-17
Study Completion Date2023-12-01

Study Record Updates

Study Start Date2021-09-17
Study Completion Date2023-12-01

Terms related to this study

Additional Relevant MeSH Terms

  • Preterm Premature Rupture of Membrane
  • Amniotic Fluid Leakage