RECRUITING

Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Personalized medicine is a concept in which medical care is individualized to a patient based on their unique characteristics, including comorbidities, demographics, genetics, and microbiome. After major surgery, some patients are at increased risk of opioid dependence. By identifying unique genetic and microbiome markers, clinicians may potentially identify individual risk factors for opioid dependence. By identifying these high risk patients early-on, personalized interventions may be applied to these patients in order to reduce the incidence of opioid-dependence.

Official Title

Using Genomics and Gut Microbiome Data to Predict Postoperative Opioid Use in Patients Undergoing Lower Extremity Joint Replacement

Quick Facts

Study Start:2021-07-19
Study Completion:2023-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04974463

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * patient undergoing unilateral knee or hip arthroplasty
  1. * refusal to consent
  2. * lack of independent decision-making capacity
  3. * inability to communicate effectively with research personnel
  4. * if patient received antibiotics within the last 3 months prior to surgery

Contacts and Locations

Study Contact

Rodney A Gabriel, MD, MAS
CONTACT
858-663-7747
ragabriel@health.ucsd.edu

Study Locations (Sites)

University of California San Diego
La Jolla, California, 92037
United States

Collaborators and Investigators

Sponsor: University of California, San Diego

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-07-19
Study Completion Date2023-12-31

Study Record Updates

Study Start Date2021-07-19
Study Completion Date2023-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Joint Pain
  • Chronic Pain
  • Opioid Use