RECRUITING

A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.

Official Title

A Pilot Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms

Quick Facts

Study Start:2022-01-03
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04981821

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age ≥60 years (conventional definition of older age in clinical trials of MN)
  2. * Have a diagnosis of MN
  3. * Planned for or receiving outpatient cancer-directed treatments (patients receiving consolidative or maintenance outpatient therapies after induction chemotherapy are allowed to enroll)
  4. * English speaking
  5. * Eastern Cooperative Oncology Group (ECOG) performance status of 0-3
  6. * No medical contraindications for exercise per oncologist
  7. * Able to walk 4 meters as part of Short Physical Performance Battery measured walk (with or without assistive device)
  8. * Able to provide informed consent
  1. * Physical, psychological, or social impairments that would interfere with patient's ability to participate in the study or participate in the intervention, as determined by the PI or the treating team

Contacts and Locations

Study Contact

Kah Poh Loh
CONTACT
585-275-5863
kahpoh_loh@urmc.rochester.edu
Terri Lloyd
CONTACT
585-276-5652
terri_lloyd@urmc.rochester.edu

Principal Investigator

Kah Poh Loh
PRINCIPAL_INVESTIGATOR
University of Rochester

Study Locations (Sites)

University of Rochester Medical Center/Wilmot Cancer Institute
Rochester, New York, 14642
United States

Collaborators and Investigators

Sponsor: University of Rochester

  • Kah Poh Loh, PRINCIPAL_INVESTIGATOR, University of Rochester

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-01-03
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2022-01-03
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • mobile health exercise intervention
  • Myeloid Neoplasm
  • GO-EXCAP

Additional Relevant MeSH Terms

  • Cancer
  • Myeloid Neoplasm