Xenon MRI Pulm Hypertension

Description

The overall objective outlined in this study is to determine how pulmonary vascular remodeling in PAH at a cellular and pathological level is associated with changes in gas exchange physiology and hemodynamics (monitored with 129Xe MRI/MRS) and how these signals change with disease progression or treatment.

Conditions

Pulmonary Hypertension, Pulmonary Arterial Hypertension

Study Overview

Study Details

Study overview

The overall objective outlined in this study is to determine how pulmonary vascular remodeling in PAH at a cellular and pathological level is associated with changes in gas exchange physiology and hemodynamics (monitored with 129Xe MRI/MRS) and how these signals change with disease progression or treatment.

Xenon MRI in Pulmonary Hypertension

Xenon MRI Pulm Hypertension

Condition
Pulmonary Hypertension
Intervention / Treatment

-

Contacts and Locations

Durham

Duke University Medical Center, Durham, North Carolina, United States, 27710

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to 75 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Bastiaan Driehuys,

    Sudarshan Rajagopal, MD, PhD, PRINCIPAL_INVESTIGATOR, Duke University

    Study Record Dates

    2026-08-30