RECRUITING

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

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Conditions

Survivors of Childhood CancerBladder Dysfunction

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.

Official Title

Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

Quick Facts

Study Start:2021-06-02
Study Completion:2026-07-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04993859

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:5 Years to 13 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Children aged 5-13 years old
  2. * A history of cancer
  3. * Treatment with a chemotherapy regimen including VCR and/or DOX
  4. * Completion of chemotherapy at least one year prior to study enrollment and survey completion.
  1. * Patients with a:
  2. * Primary pelvic tumor
  3. * Pelvic irradiation
  4. * Pre-existing bladder/bowel dysfunction
  5. * Spinal defects
  6. * Neurologic disorder
  7. * Neuro-oncologic tumor or brain metastasis
  8. * Cyclophosphamide or ifosfamide therapy

Contacts and Locations

Study Contact

Gemma Beltran
CONTACT
(720) 777-4418
gemma.beltran@childrenscolorado.org

Principal Investigator

Nicholas Cost, MD
PRINCIPAL_INVESTIGATOR
Children's Hospital Colorado

Study Locations (Sites)

Children's Hospital Colorado
Aurora, Colorado, 80045
United States

Collaborators and Investigators

Sponsor: University of Colorado, Denver

  • Nicholas Cost, MD, PRINCIPAL_INVESTIGATOR, Children's Hospital Colorado

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-06-02
Study Completion Date2026-07-09

Study Record Updates

Study Start Date2021-06-02
Study Completion Date2026-07-09

Terms related to this study

Additional Relevant MeSH Terms

  • Survivors of Childhood Cancer
  • Bladder Dysfunction