RECRUITING

Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators recently observed that up to 25% of women with X-linked adrenoleukodystrophy (ALD) have moderate to severe Restless Leg Syndrome (RLS). In this study, the investigators aim to estimate the prevalence of RLS among women with ALD and to assess whether pramipexole improves RLS symptoms as well as sleep and gait measures in women with ALD.

Official Title

Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy: A Key to Improving Sleep and Gait Performance

Quick Facts

Study Start:2023-04-01
Study Completion:2025-11-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05003648

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Women of any ethnic origin.
  2. 2. Ability to provide verbal consent
  3. 3. A willingness and ability to comply with study procedures.
  4. 4. Age 18-75 years
  5. 5. Metabolically or genetically confirmed diagnosis of ALD
  1. 1. Inflammatory brain demyelination

Contacts and Locations

Study Contact

Riya Saxena
CONTACT
603-674-6743
rsaxena2@mgh.harvard.edu

Principal Investigator

Florian S Eichler, MD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital
Boston, Massachusetts, 02114
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Florian S Eichler, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-04-01
Study Completion Date2025-11-01

Study Record Updates

Study Start Date2023-04-01
Study Completion Date2025-11-01

Terms related to this study

Additional Relevant MeSH Terms

  • Adrenoleukodystrophy
  • Restless Legs Syndrome