RECRUITING

Open Label Placebo to Reduce Prescription Opioid Use

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of the proposed study is to examine the efficacy of using an honest placebo to relieve pain for patients with an acute pain condition. People with acute pain will receive their standard dose of opioid medication for pain management. In addition, some people will be asked to take placebo pills, honestly described as placebos, as well. Patients will answer a few short questions over the phone once per day for seven days about pain and opioid use. The investigators hypothesize that participants in the open label placebo group will take fewer opioids and have less pain than those in the treatment as usual group.

Official Title

Acute Pain Treatment: A Randomized Controlled Trial Examining Opioids and Open Placebo

Quick Facts

Study Start:2021-12-09
Study Completion:2024-02-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05014230

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Michael H Bernstein, PhD
CONTACT
401-863-7688
michael_bernstein@brown.edu
Francesca Beaudoin, MD PhD
CONTACT
401-519-0330
Francesca_Beaudoin@brown.edu

Principal Investigator

Michael H Bernstein, PhD
PRINCIPAL_INVESTIGATOR
Brown University

Study Locations (Sites)

Lifespan Hospital System
Providence, Rhode Island, 02912
United States

Collaborators and Investigators

Sponsor: Brown University

  • Michael H Bernstein, PhD, PRINCIPAL_INVESTIGATOR, Brown University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-12-09
Study Completion Date2024-02-01

Study Record Updates

Study Start Date2021-12-09
Study Completion Date2024-02-01

Terms related to this study

Keywords Provided by Researchers

  • pain
  • placebo
  • analgesia
  • opioid

Additional Relevant MeSH Terms

  • Acute Pain