Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

Description

The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute. This information will be used to identify helpful tests to diagnose individuals at risk for developing difficulties with thinking and memory due to their cancer treatments.

Conditions

Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change, Chemo-brain, Chemo Fog, Chemotherapy Effect, Cognitive Decline

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute. This information will be used to identify helpful tests to diagnose individuals at risk for developing difficulties with thinking and memory due to their cancer treatments.

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy

Condition
Neoplasm, Colorectal
Intervention / Treatment

-

Contacts and Locations

Fort Wayne

Parkview Cancer Institute, Fort Wayne, Indiana, United States, 46845

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Signed written informed consent must be obtained and documented according to International Conference on Harmonisation (ICH)- Good Clinical Practice (GCP), the local regulatory requirements, and permission to use private health information in accordance with the Health Insurance Portability and Accountability Act (HIPAA) prior to study-specific screening procedures. Must be able to provide study-specific informed consent prior to study entry.
  • * A histologically-confirmed colorectal tumor
  • * Patients who will be treated with cytotoxic chemotherapies including Capecitabine, Oxaliplatin, 5 fluorouracil, and Irinotecan are eligible.
  • * Patients must not have received cytotoxic chemotherapy previous to enrollment.
  • * Prior administration of anti-cancer chemotherapy, radiotherapy, immunotherapy, or investigational agents
  • * Patients having mental incompetence as assessed by study PI, which would hinder completion of the surveys
  • * Pregnant or breastfeeding
  • * Any known brain metastases
  • * Non-English speaking patients
  • * Patients who have been diagnosed with any neuro-cognitive disorder including traumatic brain injuries, Alzheimer's disease, Parkinson's disease, Huntington's disease, and Creutzfeldt-Jakob disease.
  • * Patients deemed inappropriate to participate in this study by the study PI or coordinator will be excluded.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Joseph McCollom,

Joseph McCollom, DO, PRINCIPAL_INVESTIGATOR, Parkview Health

Study Record Dates

2030-10