RECRUITING

Economic Incentives and vDOT for Latent Tuberculosis Infection

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to evaluate a novel and scalable intervention that combines Video Directly Observed Therapy (vDOT) and financial incentives to promote completion of treatment for latent tuberculosis. Adult participants who are initiating treatment for latent tuberculosis will be recruited from the Baltimore City Health Department. The primary hypothesis is that the incentive intervention will increase the percentage of participants that complete the treatment for latent tuberculosis above the completion rates of participants receiving usual care.

Official Title

Economic Incentives and Video Directly Observed Therapy to Promote Adherence to Latent Tuberculosis Infection

Quick Facts

Study Start:2022-02-07
Study Completion:2026-10-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05022862

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years old or older,
  2. * diagnosed with latent TB and determined to be appropriate for latent TB treatment by participants clinicians
  3. * reside in Baltimore metro area
  4. * speaks English or Spanish, or a language for which there is a short form available via the Johns Hopkins Medicine Institutional Review Board
  5. * prescribed 3 months Isoniazid/Rifapentine, prescribed 3 months Isoniazid/Rifampin, or 4 months Rifampin
  1. * younger than 18 years old
  2. * diagnosed with active TB
  3. * prescribed an alternative treatment regimen for latent TB
  4. * pregnant women (as determined by non-study directed clinical evaluation; BCHD performs urine pregnancy testing on women of child bearing age when indicated)
  5. * participant's spoken language does not have a translated long or short consent form

Contacts and Locations

Study Contact

Principal Investigator
CONTACT
443-287-0401
mshah28@jhmi.edu

Principal Investigator

Maunank Shah, MD, PhD
PRINCIPAL_INVESTIGATOR
Johns Hopkins University

Study Locations (Sites)

Baltimore City Health Department, and Baltimore metropolitan area clinics and health departments
Baltimore, Maryland, 21205
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Maunank Shah, MD, PhD, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-02-07
Study Completion Date2026-10-15

Study Record Updates

Study Start Date2022-02-07
Study Completion Date2026-10-15

Terms related to this study

Keywords Provided by Researchers

  • Video Directly Observed Therapy

Additional Relevant MeSH Terms

  • Latent Tuberculosis