RECRUITING

Long-term Follow-up of Subjects Treated with CAR T Cells

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a single site, non-randomized, open-label, long-term safety and efficacy follow-up study for Phase 1 studies that evaluate the safety and efficacy of CAR T cells: NCT05660369 (DF/HCC# 22-175) and NCT06026319 (DF/HCC# 23-474).

Official Title

Long-term Follow-up of Subjects Treated with CAR T Cells

Quick Facts

Study Start:2023-08-07
Study Completion:2039-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05024175

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Provision of voluntary written informed consent by subject
  2. * CAR T cells were administered in DF/HCC IRB corresponding main study
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Matthew J Frigault, MD
CONTACT
617-643-6175
mfrigault@mgb.org

Principal Investigator

Matthew J Frigault, MD
PRINCIPAL_INVESTIGATOR
Massachusetts General Hospital

Study Locations (Sites)

Massachusetts General Hospital
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Massachusetts General Hospital

  • Matthew J Frigault, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-07
Study Completion Date2039-08-01

Study Record Updates

Study Start Date2023-08-07
Study Completion Date2039-08-01

Terms related to this study

Keywords Provided by Researchers

  • Long-Term Follow-up to CAR-T Cells
  • Follow-up Studies

Additional Relevant MeSH Terms

  • Long Term Adverse Effects
  • CAR-T
  • Duty to Follow Up
  • Adult
  • Progression-Free Survival
  • Disease-Free Survival
  • Overall Survival