Exercise Preconditioning in Ovarian Cancer

Description

The purpose of this study is to determine if exercise preconditioning can mitigate the off target effects of chemotherapy treatment on measures of cardiovascular function, peripheral neuropathy, and quality of life.

Conditions

Ovarian Cancer

Study Overview

Study Details

Study overview

The purpose of this study is to determine if exercise preconditioning can mitigate the off target effects of chemotherapy treatment on measures of cardiovascular function, peripheral neuropathy, and quality of life.

Effect of Exercise Preconditioning in Ovarian Cancer on Treatment-Related Cardiotoxicity

Exercise Preconditioning in Ovarian Cancer

Condition
Ovarian Cancer
Intervention / Treatment

-

Contacts and Locations

Charlottesville

University of Virginia University Hospital, Charlottesville, Virginia, United States, 22903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 years or over
  • * Presumed diagnosis of ovarian cancer and a planned chemotherapy regimen of a taxane and carboplatin with or without VEGF inhibition
  • * Physician clearance for exercise training
  • * Any patient unable/unwilling to cooperate with all study protocols
  • * Cancer recurrence
  • * Previous treatment with chemotherapy in the last 5-years
  • * Medical/orthopedic co-morbidities that preclude exercise training
  • * Significant heart, liver, kidney, blood, or respiratory disease precluding exercise participation
  • * Peripheral vascular disease
  • * Acute infectious disease or history of chronic infections

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Virginia,

Siddhartha S Angadi, PhD, PRINCIPAL_INVESTIGATOR, University of Virginia

Study Record Dates

2024-10