TERMINATED

Exercise Preconditioning in Ovarian Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine if exercise preconditioning can mitigate the off target effects of chemotherapy treatment on measures of cardiovascular function, peripheral neuropathy, and quality of life.

Official Title

Effect of Exercise Preconditioning in Ovarian Cancer on Treatment-Related Cardiotoxicity

Quick Facts

Study Start:2021-10-21
Study Completion:2025-06-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:TERMINATED

Study ID

NCT05029154

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18 years or over
  2. * Presumed diagnosis of ovarian cancer and a planned chemotherapy regimen of a taxane and carboplatin with or without VEGF inhibition
  3. * Physician clearance for exercise training
  1. * Any patient unable/unwilling to cooperate with all study protocols
  2. * Cancer recurrence
  3. * Previous treatment with chemotherapy in the last 5-years
  4. * Medical/orthopedic co-morbidities that preclude exercise training
  5. * Significant heart, liver, kidney, blood, or respiratory disease precluding exercise participation
  6. * Peripheral vascular disease
  7. * Acute infectious disease or history of chronic infections

Contacts and Locations

Principal Investigator

Siddhartha S Angadi, PhD
PRINCIPAL_INVESTIGATOR
University of Virginia

Study Locations (Sites)

University of Virginia University Hospital
Charlottesville, Virginia, 22903
United States

Collaborators and Investigators

Sponsor: University of Virginia

  • Siddhartha S Angadi, PhD, PRINCIPAL_INVESTIGATOR, University of Virginia

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-10-21
Study Completion Date2025-06-04

Study Record Updates

Study Start Date2021-10-21
Study Completion Date2025-06-04

Terms related to this study

Keywords Provided by Researchers

  • Cardiotoxicity
  • Ovarian Cancer
  • Exercise Training
  • Chemotherapy
  • Cardiovascular toxicity ovarian cancer chemotherapy

Additional Relevant MeSH Terms

  • Ovarian Cancer