Improving Ventilatory Capacity in Those With Chronic High Level SCI

Description

The purpose of this study is to find out if taking the drug Buspar will increase breathing capacity in individuals with spinal cord injuries.

Conditions

Spinal Cord Injuries

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this study is to find out if taking the drug Buspar will increase breathing capacity in individuals with spinal cord injuries.

Improving Ventilatory Capacity in Those With Chronic High Level SCI

Improving Ventilatory Capacity in Those With Chronic High Level SCI

Condition
Spinal Cord Injuries
Intervention / Treatment

-

Contacts and Locations

Cambridge

Spaulding Hospital Cambridge, Cambridge, Massachusetts, United States, 02138

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Chronic high-level SCI (at least 24-months post injury)
  • * Age 18 to 50 years.
  • * Medically stable
  • * Spinal Cord Injury ≥T3
  • * American Spinal Injury Association grade A or B or C.
  • * Able to perform arm crank exercise.
  • * Cardiomyopathy
  • * High blood pressure( \>140/90 mmHg or you are taking high blood pressure medication)
  • * Significant irregular heartbeat
  • * Heart disease
  • * Chronic lung disease (COPD, bronchitis)
  • * Current use of cardioactive or antidepressant drugs
  • * Family history of significant irregular heart beat or sudden cardiac death
  • * Orthostatic hypotension (symptomatic fall in blood pressure \>30 mmHg when upright)
  • * Current grade 2 or greater pressure ulcers at relevant contact site
  • * Neurological disease (stroke, peripheral neuropathy, myopathy)
  • * Arm or shoulder conditions that limit ability to perform arm crank exercise
  • * History of bleeding disorder, diabetes, kidney disease, cancer, other neurological disease
  • * Recent weigh change (greater than 10 pounds)
  • * Regular use of tobacco
  • * Intrathecal baclofen pump,
  • * Current use of cardioactive, antidepressant, other sedating agents
  • * Suicidal ideation
  • * Pregnant and/or breastfeeding women.

Ages Eligible for Study

18 Years to 50 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Spaulding Rehabilitation Hospital,

Study Record Dates

2024-11-29