RECRUITING

Effect of Early Administration of TXA in Adult Hip Fractures

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center. It is well established in the orthopedic literature that tranexamic acid (TXA) decreases blood loss and need for postoperative blood transfusion in hip fracture patients as well as total joint arthroplasty patients. A typical dosing pattern, and the dosing pattern employed at our institution, is 1 gram IV infused prior to incision followed by 1 gram IV infused at the time of wound closure.

Official Title

Does Early Administration of Tranexamic Acid Decrease Perioperative Blood Loss in Addition to Intraoperative Tranexamic Acid for Hip Fracture Patients?

Quick Facts

Study Start:2021-09-01
Study Completion:2022-07-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05047133

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 1. All adult (18 years old or older) hip fracture patients presenting with an acute hip fracture and undergoing operative fixation
  1. 1. Polytrauma patients
  2. 2. Previous operation on the ipsilateral hip
  3. 3. Patients with coagulopathies (Factor V Leiden, Sickle Cell Anemia, Etc.)
  4. 4. Patients with \< 6-month history of thromboembolic event (DVT/PE), Stroke, Cardiac Stents, or Myocardial Infarction (MI)
  5. 5. History of seizure disorder
  6. 6. Patients on birth control
  7. 7. Pregnant Women
  8. 8. Prisoners
  9. 9. Active thromboembolic disease (DVT/PE, MI, Stroke)

Contacts and Locations

Study Contact

Jacob Hinkley, DO, MS
CONTACT
810-606-5669
jacob.hinkley2@ascension.org
Jacob Lytle, DO
CONTACT
810-606-5669
jacob.lytle@ascension.org

Study Locations (Sites)

Ascension Genesys Hospital
Grand Blanc, Michigan, 48439
United States

Collaborators and Investigators

Sponsor: Ascension Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-01
Study Completion Date2022-07-01

Study Record Updates

Study Start Date2021-09-01
Study Completion Date2022-07-01

Terms related to this study

Additional Relevant MeSH Terms

  • Postoperative Blood Loss