Ketorolac vs Oxycodone for Great Toe Arthrodesis

Description

This study reviews if taking ketorolac, after a joint fusion procedure, can decrease the need for taking oxycodone (standard of care) for pain relief. The study also investigates if ketorolac affects bone healing after surgery.

Conditions

Arthrodesis

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Study Overview

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Study Details

Study overview

This study reviews if taking ketorolac, after a joint fusion procedure, can decrease the need for taking oxycodone (standard of care) for pain relief. The study also investigates if ketorolac affects bone healing after surgery.

Effect of Ketorolac Administration on Post-operative Narcotic Utilization and Union Rates in Great Toe Arthrodesis

Ketorolac vs Oxycodone for Great Toe Arthrodesis

Condition
Arthrodesis
Intervention / Treatment

-

Contacts and Locations

Baltimore

Amy Loveland, Baltimore, Maryland, United States, 21218

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 - 75 years.
  • * Women of childbearing potential must have a negative serum or urine pregnancy test results within 24 hours before the first dose of ketorolac.
  • * Primary elective great toe MTP arthrodesis (CPT 28750). Other forefoot procedures often performed in conjunction with toe fusion will be included (CPT codes 28308, 28285, 28270).
  • * Chronic pain syndrome, CRPS or fibromyalgia
  • * Revision procedures
  • * Use of allograft bone at the fusion site
  • * Tobacco use
  • * Diabetes
  • * Narcotic abuse or IV drug abuse
  • * Any CPT codes involving the midfoot, hindfoot, and/or ankle
  • * Unable to take NSAIDs secondary to medical comorbidities such as kidney disease (impaired renal function with CrCl ≤ 50 ml/min) or gastric ulcers
  • * Weight \< 50 kg
  • * Does not speak or read English
  • * If pregnant or planning to become pregnant or breastfeeding
  • * Non-independent dweller (prisoner)

Ages Eligible for Study

18 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Medstar Health Research Institute,

Study Record Dates

2024-07-31