ED Observation for Opioid Use Disorder

Description

This is a multicenter, randomized clinical comparative effectiveness trial (RCT) in which patients with untreated OUD presenting to a Northwell Health Emergency Department (ED), NYULH-Brooklyn, NYULH-Tisch, and Bellevue Hospital will be randomized (1:1) to be managed clinically through either a standard ED visit or an extended visit through ED observation (EDOU).

Conditions

Opiod Use Disorder

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Study Overview

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Study Details

Study overview

This is a multicenter, randomized clinical comparative effectiveness trial (RCT) in which patients with untreated OUD presenting to a Northwell Health Emergency Department (ED), NYULH-Brooklyn, NYULH-Tisch, and Bellevue Hospital will be randomized (1:1) to be managed clinically through either a standard ED visit or an extended visit through ED observation (EDOU).

Measuring Improvement in the Quality of Emergency Department-initiated Treatment for Opioid Use Disorders Using Observation

ED Observation for Opioid Use Disorder

Condition
Opiod Use Disorder
Intervention / Treatment

-

Contacts and Locations

Newark

Rutgers University-University Hospital, Newark, New Jersey, United States, 07103

Brooklyn

NYULH-Brooklyn, Brooklyn, New York, United States, 11220

New Hyde Park

Northwell Health - Long Island Jewish Medical Center, New Hyde Park, New York, United States, 11040

New York

Bellevue, New York, New York, United States, 10016

New York

NYULH-Tisch, New York, New York, United States, 10016

Staten Island

Northwell Health - Staten Island University Hospital, Staten Island, New York, United States, 10305

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Is 18 years of age or older
  • * Is able to speak English sufficiently to understand study procedures
  • * Has a history of non-medical opioid use
  • * Is a potential candidate for ED-based MOUD treatment initiation and referral at the site as confirmed by clinical staff
  • * s not receiving MOUD through ongoing formal addiction treatment or pain management at the time of index ED visit
  • * Is willing to receive either standard ED care or enhanced ED care in EDOU depending on random assignment
  • * Presents to the ED during study screening hours
  • * Unwilling or unable to provide written/electronic informed consent/HIPAA Authorization for research procedures, including research visits at baseline and Day 30 and Day 90, and/or consent for the release of health records and data matching for a period of 2 years following enrollment and 1 year prior to enrollment.
  • * Currently in jail, prison or any inpatient overnight facility as required by court of law or have pending legal action or that could prevent participation in the study
  • * Presents from a medical-based extended care facility (e.g., skilled nursing facility)
  • * Previous participation in the current study
  • * Inadequate locator information (unable or unwilling to provide one unique mean of contact).
  • * Has acute, severe medical, psychiatric, or concurrent substance use problem or meets other criteria that would exclude the patient (clinically) from placement in EDOU according to EDOU placement clinical protocols.

Ages Eligible for Study

18 Years to 100 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

NYU Langone Health,

Ryan McCormack, MD, PRINCIPAL_INVESTIGATOR, NYU Langone Health

Study Record Dates

2025-07-31