Delirium Reduction With Ramelteon

Description

The overall purpose of this study is to identify a medication that might treat and/or prevent delirium in intensive care unit (ICU). Currently, there is no proven medical therapy for prevention or treatment of delirium. Ramelteon is a medication approved for insomnia. We hypothesize that ramelteon may help regulate the day/night cycle and decrease ICU delirium.

Conditions

Delirium

Talk to us

Study Overview

On this page

Study Details

Study overview

The overall purpose of this study is to identify a medication that might treat and/or prevent delirium in intensive care unit (ICU). Currently, there is no proven medical therapy for prevention or treatment of delirium. Ramelteon is a medication approved for insomnia. We hypothesize that ramelteon may help regulate the day/night cycle and decrease ICU delirium.

Delirium Reduction With Ramelteon

Delirium Reduction With Ramelteon

Condition
Delirium
Intervention / Treatment

-

Contacts and Locations

Nashville

Centennial Medical Center, Nashville, Tennessee, United States, 37205

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Medical or surgical ICU patient
  • * Ability to take oral or nasogastric tube within 48 hours of admission to ICU
  • * Expected ICU length of stay and life expectancy at least 48 hours
  • * Patient or POA capable of signing informed consent within 48 hours of ICU admission
  • * Past medical history includes cirrhosis
  • * Active alcohol withdrawal
  • * Patients taking fluvoxamine prior to admission
  • * Self-reported hypersensitivity to ramelteon
  • * Incarcerated patients
  • * Pregnant patients
  • * Patients with acute neurological conditions including brain abscess, head bleed, meningitis
  • * Patients who are transferred from an outside hospital where they have resided for greater than 4 days
  • * Non-English speaking patients
  • * Hearing-impaired patients requiring sign language for communication
  • * Visually-impaired patients

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Centennial Medical Center,

Jennifer Johnson, MD, PRINCIPAL_INVESTIGATOR, Centennial Medical Center

Study Record Dates

2025-12