Arrhythmia Detection After MI

Description

Patients post acute myocardial infarction (AMI) have a high risk of mortality but the use of an implantable defibrillator in the early aftermath of an AMI has not been shown to improve patients' survival. The VEST trial recently demonstrated an improved overall survival in post AMI patients with the use of a wearable defibrillator. The same improvement was not demonstrated for the risk of sudden cardiac death. Monitoring patients after AMI using an implantable cardiac monitor (ICM) may document findings that can impact patient management and eventually improve their outcomes. We are therefore conducting the AID MI trial to examine the impact of ICM on patient management in the post AMI setting.

Conditions

Acute Myocardial Infarction

Study Overview

Study Details

Study overview

Patients post acute myocardial infarction (AMI) have a high risk of mortality but the use of an implantable defibrillator in the early aftermath of an AMI has not been shown to improve patients' survival. The VEST trial recently demonstrated an improved overall survival in post AMI patients with the use of a wearable defibrillator. The same improvement was not demonstrated for the risk of sudden cardiac death. Monitoring patients after AMI using an implantable cardiac monitor (ICM) may document findings that can impact patient management and eventually improve their outcomes. We are therefore conducting the AID MI trial to examine the impact of ICM on patient management in the post AMI setting.

Arrhythmia Detection After Myocardial Infarction Trial

Arrhythmia Detection After MI

Condition
Acute Myocardial Infarction
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

UPMC Presbyterian Hospital, Pittsburgh, Pennsylvania, United States, 15213

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adults, age 18 years or older
  • * AMI (STEMI and NSTEMI)
  • * Willing to give written informed consent
  • * Expected discharge from hospital within 7 days of AMI
  • * Willing to receive ICM insertion within 21 days of index AMI
  • * Existing pacemaker, ICD, ICM, or any other implantable cardiac electronic device
  • * Pregnant
  • * Index AMI was more than 21 days
  • * Unwilling/cannot insert ICM within 21 days post AMI
  • * Planned ICD implant, planned CABG or any open-heart surgery (e.g. for severe valvular disease)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Samir Saba,

Samir F Saba, MD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh Medical Center

Study Record Dates

2025-10