CYP2C19 Variants and Limonene Metabolism

Description

The investigators will examine whether a non-invasive screening tool for CYP2C19 genetic variants can be developed by measuring limonene metabolism.

Conditions

CYP2C19 Genetic Variants

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Study Overview

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Study Details

Study overview

The investigators will examine whether a non-invasive screening tool for CYP2C19 genetic variants can be developed by measuring limonene metabolism.

Functional Consequences of CYP2C19 Variants on Limonene Metabolism in Humans

CYP2C19 Variants and Limonene Metabolism

Condition
CYP2C19 Genetic Variants
Intervention / Treatment

-

Contacts and Locations

Stanford

Stanford School of Medicine, Stanford, California, United States, 94305

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age range: Greater than 18 years and less than 45 years.
  • * Gender: Male or Female
  • * Ethnicities: East Asian
  • * Pregnant and/or Breastfeeding
  • * previous allergic reaction to limonene, citrus fruits, bovine gelatin, glycerin
  • * past medical history of cerebrovascular or cardiovascular disease
  • * veganism
  • * history of chest pain or shortness of breath in the past month
  • * certain medications that are CYP2C19 substrates or CYP2C19 inhibitors
  • * Non-East Asian descent
  • * age less than 18 y.o or age greater than 45 y.o

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Stanford University,

Study Record Dates

2024-12