RECRUITING

Locomotor Recovery and Compensation Post-stroke (LRC)

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.

Official Title

Locomotor Recovery and Compensation Post-stroke (LRC)

Quick Facts

Study Start:2021-09-01
Study Completion:2026-02-28
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05081713

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 85 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * individuals early post-stroke (\<15-30 days)
  2. * first ever stroke
  3. * unilateral hemiparesis
  4. * currently receiving inpatient rehabilitation
  5. * ability to follow 1-step commands
  6. * provision of informed consent
  7. * medical clearance from the rehabilitation physician to participate. \\
  1. * uncontrolled cardiovascular, metabolic or respiratory disease that limits exercise participation (e.g., congestive heart failure, resting blood pressure \> 200/110 mmHg, uncontrolled diabetes, end-stage renal disease)
  2. * absolute criteria for termination of exercise testing during initial and repeated ECG testing during graded exercise testing using ACSM guidelines .
  3. * other orthopedic or neurological disorder that limited walking prior to stroke

Contacts and Locations

Study Contact

Thomas G Hornby
CONTACT
3173292353
tghornby@Iu.edu
Chris Henderson
CONTACT
3173292353
henderce@iu.edu

Principal Investigator

Thomas G Hornby
PRINCIPAL_INVESTIGATOR
Indiana University School of Medicine

Study Locations (Sites)

Rehabilitation Hospital of Indiana
Indianapolis, Indiana, 46254
United States

Collaborators and Investigators

Sponsor: Indiana University

  • Thomas G Hornby, PRINCIPAL_INVESTIGATOR, Indiana University School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-01
Study Completion Date2026-02-28

Study Record Updates

Study Start Date2021-09-01
Study Completion Date2026-02-28

Terms related to this study

Additional Relevant MeSH Terms

  • Stroke