ACTIVE_NOT_RECRUITING

PENG vs. FIC Block for Hip Fracture ED Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Ultrasound-guided nerve blocks are an important tool for treating pain due to orthopedic injury in the ED. They provide long lasting, opioid-sparing pain relief that is generally safe and well-tolerated by patients1. Elderly patients with hip fractures commonly present to the ED, and their injury can be painful. Commonly used opioid pain regimens can have deleterious side effects, especially in elderly patients, like somnolence, delirium, hypotension and respiratory depression. The fascia iliaca compartment (FIC) block has become a familiar technique to emergency physicians as a pain control treatment for hip fractures. The pericapsular nerve group (PENG) block has recently been proposed as a novel method to treat pain due to hip, acetabular and pelvic fracture by targeting the terminal sensory articular nerve branches of the femoral nerve (FN), obturator nerve (ON), and accessory obturator nerve (AON). At this time there has been no study comparing the efficacy of the two nerve blocks, PENG and FIC. This aim of this study is to compare the efficacy of the PENG block (20mL of Bupivacaine 0.50%) to that of the FIC block (40mL of Bupivacaine 0.25%) for patients with hip fractures in the ED. Our hypothesis is that PENG will demonstrate analgesia that is non-inferior to FIC. Subjective pain scores on a scale of 0 to 10 will be assessed before and after the block. All subjects will receive 4mg of morphine after consent and prior to the block.

Official Title

Pericapsular Nerve Group (PENG) Block vs. the Fascia Iliaca Compartment (FIC) Block for Patients With Isolated Hip Fractures in the Emergency Department

Quick Facts

Study Start:2021-10-20
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05102760

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 110 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult Emergency Medicine Patients over 18 years of age
  2. * Isolated hip fracture, intertrocanteric or more proximal
  3. * Pain score 5 or greater on a scale of 0 to 10 just prior to nerve block placement
  1. * Patients with multi-system trauma
  2. * People who are unable to communicate their level of pain\\
  3. * Pregnant patients
  4. * Pediatric Patients (less than 18 years of age)
  5. * Intoxicated Patients
  6. * Abnormal Vital Signs (HR\>120bpm, MAP \<65, Pulse Ox \<95%)
  7. * Patients on long term systemic opioid analgesia
  8. * Allergy to amide local anesthetics

Contacts and Locations

Principal Investigator

Lawrence Haines, MD
PRINCIPAL_INVESTIGATOR
Maimonides Medical Center

Study Locations (Sites)

Maimonides Medical Center
Brooklyn, New York, 11209
United States

Collaborators and Investigators

Sponsor: Antonios Likourezos

  • Lawrence Haines, MD, PRINCIPAL_INVESTIGATOR, Maimonides Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-10-20
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2021-10-20
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • Pain
  • Hip Fracture
  • Nerve Block
  • Ultrasound

Additional Relevant MeSH Terms

  • Pain
  • Hip Fracture