Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain

Eligibility Criteria

• * Age \>= 21 years old
• * Able to provide informed consent
• * Primary complaint of chronic knee pain for at least 1 year that interferes with functional activities
• * Current pain score on visual analog scale (VAS) intensity ≥60 mm
• * One of two groups: 1) Non-operated knee pain patients who want to pursue alternative therapies and delay surgery or are not candidates for knee arthroplasty based on age, frailty, non-operable condition, or poor outcome with other side arthroplasty, or 2) Post traumatic knee pain patients with history of surgical repair (such as meniscal or ligament repair).
• * Radiologic confirmation (x-ray/MRI/CT) of Kellgren-Lawrence OA grade of 2 (mild) or 3 (moderate) or 4 (severe) noted within 6 months for the index knee
• * Continued pain in the target knee despite at least 3 months of conservative treatments with documented failure of physical therapy and standard conservative therapy, including trials of at least two different classes of analgesic medication
• * Failure of one or more prior interventional pain procedures such intraarticular corticosteroid or hyaluronidase knee injections, cooled radiofrequency ablation therapy, or regenerative medicine or prior surgery of the knee
• * Non-English speaking
• * Douleur neuropathique 4 (DN4) score ≥4
• * Receiving opioid analgesic medication at a dose of ≥90 mg oral morphine equivalents
• * Workers' compensation or no-fault insurance
• * Signs or symptoms of active infection in the index knee joint
• * Pregnancy
• * BMI \>45
• * Presence of any contraindication for DRG stimulation, including neurological, medical, psychiatric, or social conditions.
• * Widespread pain conditions like fibromyalgia
• * Autoimmune/Inflammatory arthritic conditions such as Rheumatoid and psoriatic arthritis and other allied disorders (sjogren, felty, inflammatory bowl disease etc)
• * Collagen diseases (systemic lupus erythematosus, Scleroderma, etc)
• * Infectious arthritis
• * Evidence of prespecified joint safety conditions (eg, rapidly progressive OA, subchondral insufficiency fracture, osteonecrosis, pathologic fracture) in the index knee on screening radiographs
• * Scheduled for or anticipating any surgery during the trial period