An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

Description

The main purpose of this study is to continue to see how vonsetamig works in the body and to monitor the outcomes after kidney transplant for participants previously treated in the R5459-RT-1944 study (NCT05092347). No study drug will be given during this study.

Conditions

Chronic Kidney Disease (CKD)

Study Overview

Study Details

Study overview

The main purpose of this study is to continue to see how vonsetamig works in the body and to monitor the outcomes after kidney transplant for participants previously treated in the R5459-RT-1944 study (NCT05092347). No study drug will be given during this study.

A Noninterventional Extension Study for Patients Treated in Study R5459-RT-1944 With Vonsetamig (BCMA x CD3 Bispecific Antibody) Who Receive a Kidney Transplant

An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

Condition
Chronic Kidney Disease (CKD)
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Cedars-Sinai Medical Center, Los Angeles, California, United States, 90048

Orange

University of California Irvine, Orange, California, United States, 92868

San Francisco

Connie Frank Transplant Center at UCSF, San Francisco, California, United States, 94143

New Haven

Yale University of Medicine, New Haven, Connecticut, United States, 06520

Chicago

Comprehensive Transplant Center, Chicago, Illinois, United States, 60611

Baltimore

John Hopkins Hospital, Baltimore, Maryland, United States, 21224

New York

New York University Langone Health, New York, New York, United States, 10016

Philadelphia

Penn Transplant Institute, Philadelphia, Pennsylvania, United States, 19104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Received at least 1 dose of treatment with vonsetamig in study R5459-RT-1944 \[NCT05092347\].
  • 2. Received after acceptable crossmatching, a kidney transplant while enrolled in study R5459-RT-1944
  • 3. Willing and able to comply with clinic visits and study-related procedures
  • 4. Provide informed consent signed by study patient or legally acceptable representative
  • 1.There are no exclusion criteria for this study.

Ages Eligible for Study

18 Years to 70 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Regeneron Pharmaceuticals,

Clinical Trial Management, STUDY_DIRECTOR, Regeneron Pharmaceuticals

Study Record Dates

2027-12-24