RECRUITING

Aspiration in Acute Respiratory Failure Survivors 2

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.

Official Title

Aspiration in Acute Respiratory Failure Survivors

Quick Facts

Study Start:2021-12-15

Study Completion:2025-12-15

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05108896

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
1. Admission to an ICU. 2. Mechanical ventilation with an endotracheal tube for greater than 48 hours.	1. Likely persistent contraindications to enteral/oral nutrition administration. 2. Pre-existing history of dysphagia or aspiration. 3. Pre-existing or acute primary central or peripheral neuromuscular disorder. 4. Presence of a chronic tracheostomy (present prior to ICU admission). 5. Pre-existing head and neck cancer or surgery. 6. Coagulopathy resulting in uncontrolled nasal or pharyngeal bleeding. 7. Delirium for more than 96 hours after extubation as assessed by Confusion Assessment Method (CAM-ICU). 8. Extubated for greater than 96 hours. 9. Inability to obtain informed consent from patient or an appropriate surrogate. 10. Age \< 18 years.

Inclusion Criteria

Exclusion Criteria

1. Admission to an ICU.
2. Mechanical ventilation with an endotracheal tube for greater than 48 hours.

1. Likely persistent contraindications to enteral/oral nutrition administration.
2. Pre-existing history of dysphagia or aspiration.
3. Pre-existing or acute primary central or peripheral neuromuscular disorder.
4. Presence of a chronic tracheostomy (present prior to ICU admission).
5. Pre-existing head and neck cancer or surgery.
6. Coagulopathy resulting in uncontrolled nasal or pharyngeal bleeding.
7. Delirium for more than 96 hours after extubation as assessed by Confusion Assessment Method (CAM-ICU).
8. Extubated for greater than 96 hours.
9. Inability to obtain informed consent from patient or an appropriate surrogate.
10. Age \< 18 years.

Contacts and Locations

Study Contact

Jeff McKeehan, RN,MSN

CONTACT

3037246080

jeffrey.mckeehan@cuanschutz.edu

Principal Investigator

Marc Moss, MD

PRINCIPAL_INVESTIGATOR

University of Colorado, Denver

Study Locations (Sites)

Stanford Univerity

Stanford, California, 94305

United States

University of Colorado

Aurora, Colorado, 80045

United States

Yale University

New Haven, Connecticut, 06519

United States

Tufts Medical Center

Boston, Massachusetts, 02111

United States

Boston University

Boston, Massachusetts, 02118

United States

Collaborators and Investigators

Sponsor: University of Colorado, Denver

Marc Moss, MD, PRINCIPAL_INVESTIGATOR, University of Colorado, Denver

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-12-15

Study Completion Date2025-12-15

Study Record Updates

Study Start Date2021-12-15

Study Completion Date2025-12-15

Terms related to this study

Additional Relevant MeSH Terms

Dysphagia
Aspiration