Aspiration in Acute Respiratory Failure Survivors 2

Description

The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.

Conditions

Dysphagia, Aspiration

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Study Overview

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Study Details

Study overview

The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.

Aspiration in Acute Respiratory Failure Survivors

Aspiration in Acute Respiratory Failure Survivors 2

Condition
Dysphagia
Intervention / Treatment

-

Contacts and Locations

Stanford

Stanford Univerity, Stanford, California, United States, 94305

Aurora

University of Colorado, Aurora, Colorado, United States, 80045

New Haven

Yale University, New Haven, Connecticut, United States, 06519

Boston

Tufts Medical Center, Boston, Massachusetts, United States, 02111

Boston

Boston University, Boston, Massachusetts, United States, 02118

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Admission to an ICU.
  • 2. Mechanical ventilation with an endotracheal tube for greater than 48 hours.
  • 1. Likely persistent contraindications to enteral/oral nutrition administration.
  • 2. Pre-existing history of dysphagia or aspiration.
  • 3. Pre-existing or acute primary central or peripheral neuromuscular disorder.
  • 4. Presence of a chronic tracheostomy (present prior to ICU admission).
  • 5. Pre-existing head and neck cancer or surgery.
  • 6. Coagulopathy resulting in uncontrolled nasal or pharyngeal bleeding.
  • 7. Delirium for more than 96 hours after extubation as assessed by Confusion Assessment Method (CAM-ICU).
  • 8. Extubated for greater than 96 hours.
  • 9. Inability to obtain informed consent from patient or an appropriate surrogate.
  • 10. Age \< 18 years.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Colorado, Denver,

Marc Moss, MD, PRINCIPAL_INVESTIGATOR, University of Colorado, Denver

Study Record Dates

2025-12-15